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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
17.58
Human Site:
T146
Identified Species:
27.62
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
T146
P
D
N
F
L
M
G
T
G
R
H
C
N
K
L
Chimpanzee
Pan troglodytes
XP_522662
337
39019
T146
P
D
N
F
L
M
G
T
G
R
H
C
N
K
L
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
T146
P
D
N
F
L
M
G
T
G
R
H
C
N
K
L
Dog
Lupus familis
XP_867638
336
38749
I146
P
D
N
F
L
M
G
I
G
R
H
C
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
T176
E
N
K
N
L
T
G
T
A
R
Y
A
S
I
N
Rat
Rattus norvegicus
P97633
325
37477
N141
H
R
D
I
K
P
D
N
F
L
M
G
I
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
I146
P
D
N
F
L
M
G
I
G
R
H
C
N
K
L
Frog
Xenopus laevis
Q5BP74
415
47421
T176
E
N
K
N
L
T
G
T
A
R
Y
A
S
I
N
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
T176
E
N
K
N
L
T
G
T
A
R
Y
A
S
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
I149
P
D
N
F
L
M
G
I
G
R
H
C
N
K
L
Honey Bee
Apis mellifera
XP_393612
350
40282
I150
P
D
N
F
L
M
G
I
G
R
H
C
N
K
L
Nematode Worm
Caenorhab. elegans
P42168
341
39018
I145
P
D
N
F
L
M
G
I
G
R
H
C
N
K
L
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
I160
P
D
N
F
L
M
G
I
G
R
H
C
N
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
T176
E
N
K
N
L
T
G
T
A
R
Y
A
S
M
N
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
K231
K
Y
D
R
I
M
E
K
K
L
N
V
S
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
100
100
93.3
N.A.
26.6
0
N.A.
N.A.
93.3
26.6
26.6
N.A.
93.3
93.3
93.3
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
6.6
N.A.
N.A.
93.3
46.6
46.6
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
27
0
0
27
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% C
% Asp:
0
60
14
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
27
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
60
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
87
0
60
0
0
7
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
40
0
0
0
0
7
20
0
% I
% Lys:
7
0
27
0
7
0
0
7
7
0
0
0
0
54
0
% K
% Leu:
0
0
0
0
87
0
0
0
0
14
0
0
0
0
60
% L
% Met:
0
0
0
0
0
67
0
0
0
0
7
0
0
7
0
% M
% Asn:
0
27
60
27
0
0
0
7
0
0
7
0
60
0
27
% N
% Pro:
60
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
87
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% S
% Thr:
0
0
0
0
0
27
0
47
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
27
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _